James Kern (“Kay”) Kyser (June 18, 1905 – July 23, 1985) was a popular bandleader and radio personality of the 1930s and 1940s.

He was born in Rocky Mount, North Carolina, the son of pharmacists Paul Bynum Kyser and Emily Royster (Howell) Kyser, and a cousin of editor Vermont C. Royster. Kyser graduated from the University of North Carolina at Chapel Hill, where he was senior class president, with a Bachelor of Arts degree. Because of his popularity and enthusiasm as a cheerleader, he was invited by Hal Kemp to take over as bandleader when Kemp ventured north to further his career. He began taking clarinet lessons but was better as an entertaining announcer than a musician. He adopted the initial of his middle name as part of his stage name, for its alliterative effect.