Enzo Avitabile (born 1 March 1955) is an Italian saxophonist and singer-songwriter. He plays a fusion of World music and jazz fusion music.

He tours with his band, going under the name of Enzo Avitabile and Bottari. Bottari is a traditional rhythm from south Italy. It involves wine barrels, wooden drums, etc. Avitabile keeps the Bottari culture in mind while experimenting with fusion Jazz (sax, trumpets, etc.).

In the past he has collaborated with Pino Daniele, Edoardo Bennato, James Brown and Tina Turner, among the others. Along with Bottari, he was nominated for the prestigious 'Audience Award' in the 2005 BBC Awards for World Music.

He was born in Naples.